Pharmacology (Foundations)

Medical FoundationsAdvanced Level

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Question

What is the significance of bioavailability in pharmacology?

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Answer

Definition

Bioavailability is the fraction of an administered drug that reaches the systemic circulation unchanged. It is crucial because it determines the drug's efficacy and dosage.

Example

For instance, oral morphine has a bioavailability of about 25%, meaning only a quarter of the dose enters the bloodstream effectively.

Quick Tip

Think of bioavailability as the 'effective dose' that truly works.

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